• Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin 

      Schneider, Yannik Karl Heinz; Liaimer, Anton; Isaksson, Johan Mattias; Wilhelmsen, Oda Sofie Bye; Andersen, Jeanette Hammer; Østnes Hansen, Kine; Hansen, Espen Holst (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-20)
      The suomilide and the banyasides are highly modified and functionalized non-ribosomal peptides produced by cyanobacteria of the order Nostocales. These compound classes share several substructures, including a complex azabicyclononane core, which was previously assumed to be derived from the amino acid tyrosine. In our study we were able to isolate and determine the structures of four suomilides, ...
    • A Genetic and Chemical Perspective on Symbiotic Recruitment of Cyanobacteria of the Genus Nostoc into the Host Plant Blasia pusilla L. 

      Liaimer, Anton; Jensen, John Beck; Dittmann, Elke (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-01)
      Liverwort Blasia pusilla L. recruits soil nitrogen-fixing cyanobacteria of genus Nostoc as symbiotic partners. In this work we compared Nostoc community composition inside the plants and in the soil around them from two distant locations in Northern Norway. STRR fingerprinting and 16S rDNA phylogeny reconstruction showed a remarkable local diversity among isolates assigned to several Nostoc ...
    • Genomic Changes Associated with the Evolutionary Transitions of Nostoc to a Plant Symbiont 

      Warshan, Denis; Liaimer, Anton; Pederson, Eric; Kim, Sea-Yong; Shapiro, Nicole; Woyke, Tanja; Altermark, Bjørn; Pawlowski, Katharina; Weyman, Philip D.; Dupont, Christopher L.; Rasmussen, Ulla (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-15)
      Cyanobacteria belonging to the genus Nostoc comprise free-living strains and also facultative plant symbionts. Symbiotic strains can enter into symbiosis with taxonomically diverse range of host plants. Little is known about genomic changes associated with evolutionary transition of Nostoc from free-living to plant symbiont. Here, we compared the genomes derived from 11 symbiotic Nostoc strains ...
    • High-density cultivation of terrestrial Nostoc strains leads to reprogramming of secondary metabolome 

      Guljamow, Arthur; Kreische, Marco; Ishida, Keishi; Liaimer, Anton; Altermark, Bjørn; Bähr, Lars; Hertweck, Christian; Dittmann, Elke (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-22)
      Terrestrial symbiotic cyanobacteria of the genus <i>Nostoc</i> exhibit a large potential for the production of bioactive natural products of the nonribosomal peptide, polyketide, and ribosomal peptide classes, and yet most of the biosynthetic gene clusters are silent under conventional cultivation conditions. In the present study, we utilized a high-density cultivation approach recently developed ...
    • On the resistance of epiphytic cyanobacteria of the Kola Bay to the effects of oil hydrocarbons in the aquatic ecosystem 

      Pugovkin, Dmitry V.; Miroshnichenko, E.S.; Voskoboinikov, Grigory M.; Jensen, John Beck; Liaimer, Anton (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      The epiphytic communities of cyanobacteria of Fucus vesiculosus L. of the Kola Bay are able to bear the high amounts of the oil products in the environment. The results of studying the resistance of epiphytic cyanobacterial communities to oil pollution using both classical (cultural) and molecular-genetic methods of microbiological analysis have been presented. The objects of the study are the ...